DrLIFE3350 DrLIFE3350

03-04-2018
Biology

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Identify the mutagenic effects of deaminating agents, alkylating agents, and base analogs.

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JABARBS JABARBS

12-04-2018

All are mutagenic because they cause base substitutions, deaminating agents oxidatively deaminate bases so cytosine converted to uracil and adenine converted to hypoxanthine, uracil pairs with adenine and hypoxanthine pairs with cytosine, alkylating agents donate alkyl group to amino or keto groups altering base pair affinities

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